Nutritional intervention protocol;
Evaluation of food frequency questionnaires;
Assessment of physical activity;
Evaluation of compliance to supplemental foods;
Assessment of tolerance and adverse effects;
Biobank maintenance;
Database maintenance;
Event certification;
Lipid biomarkers;
Oxidative stress;
Biomarkers of inflammation;
Biomarkers of thrombosis;
Genetic variation in relation to intermediate and main outcomes;
Genetic and nutritional epidemiology of weight gain and obesity;
Statistical analyses;
Specific Projects:
Insulin sensitivity;
Blood pressure;
Cognitive impairment;
Vascular imaging;
Dietary polyphenols;
Dietary phytosterols;
Composition of triglyceride-rich lipoproteins;
Homocysteine;
Heavy metals and trace elements in foot nails;
Bone biomarkers;
Experimental atherosclerosis with PREDIMED diets in apoE-deficient mice;
Quality of life;
Cardiac Function.