Interests:
Human metabolism and dietary alterations in health and disease.
Fat, carbohydrate and energy metabolism, in exercise, over- and undernutrition.
Metabolic disturbances in obesity and diabetes.
Metabolic and nutritional factors affecting cognitive function.
Effects of nutrients on vascular function
Techniques:
Energy expenditure and body composition.
Hormone and metabolite assays in blood.
Metabolites and gene expression in biopsies of adipose tissue and skeletal muscle.
Measurement of whole body sensitivity to insulin, to catecholamines, and responses to single meals and dietary manipulation.
Assessing sympathoadrenal activity from plasma and urine catecholamines and microneurography of sympathetic nerves.
Non-invasive assessment of cardiovascular function.
Projects:
Dietary control of gene expression in human skeletal muscle and adipose tissue
Nutrient-gene interactions in human obesity (EU FP5).
The effects of food products on appetite, satiety and food intake (Food industry).
Dietary and lifestyle factors affecting postprandial glucose levels.
Effects of food ingredients on vascular function (Food industry)